Three Ca2+ channel inhibitors in combination limit chronic secondary degeneration following neurotrauma
نویسندگان
چکیده
منابع مشابه
Delayed treatment of secondary degeneration following acute optic nerve transection using a combination of ion channel inhibitors
Studies have shown that a combined application of several ion channel inhibitors immediately after central nervous system injury can inhibit secondary degeneration. However, for clinical use, it is necessary to determine how long after injury the combined treatment of several ion channel inhibitors can be delayed and efficacy maintained. In this study, we delivered Ca2+ entry-inhibiting P2X7 re...
متن کاملHigh Performance Sub-Diffraction Limit Three Channel Plasmonic Demultiplexer
We have proposed a new ultra-compact optical demultiplexer based on metal-insulator-metal plasmonic waveguides aperture-coupled to the ring resonators. Our proposed device has high performance, small footprint, and high potential for integration and development to more channels.
متن کاملChronic effects of neurotrauma consortium.
ISSN: 0269-9052 (Print) 1362-301X (Online) Journal homepage: http://www.tandfonline.com/loi/ibij20 Chronic effects of neurotrauma consortium David X. Cifu & Kirsty J. Dixon To cite this article: David X. Cifu & Kirsty J. Dixon (2016) Chronic effects of neurotrauma consortium, Brain Injury, 30:12, 1397-1398, DOI: 10.1080/02699052.2016.1219065 To link to this article: http://dx.doi.org/10.1080/02...
متن کاملImprovement in chronic hepatocerebral degeneration following liver transplantation.
Chronic progressive hepatocerebral degeneration with spastic paraparesis, dementia, dysarthria, ataxia, tremor, and neuropsychiatric symptoms follows long-standing portal-systemic shunting, is associated with structural changes in the central nervous system, and does not respond to conventional therapy for hepatic encephalopathy. A case of advanced chronic liver disease with severe, progressive...
متن کاملImpaired behavioral and neuropathological outcomes following blast neurotrauma
Blast-induced neurotrauma (BINT) is a major societal concern due to the complex expression of neuropathological disorders after exposure to blast. Disruptions in neuronal function, proximal in time to the blast exposure, may eventually contribute to the late emergence of the clinical deficits. Besides complications with differential clinical diagnosis, the biomolecular mechanism underlying BINT...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuropharmacology
سال: 2013
ISSN: 0028-3908
DOI: 10.1016/j.neuropharm.2013.07.034